A Practice Note discussing actions the US Food and Drug Administration (FDA) may take to prevent imports of FDA-regulated products from entering US commerce if they do not comply with requirements of the Federal Food, Drug, and Cosmetic Act (FDCA) or other laws enforced by the FDA. This Note discusses import alerts and detentions without physical examination (DWPE), various Notices of FDA Action, including Notices of Detention and Hearing and Notices of Refusal of Admission, and the FDA's ability to pursue the seizure of violative products in certain situations.