A Practice Note explaining how to start a civil appeal to the US Court of Appeals for the District of Columbia Circuit from the US District Court for the District of Columbia. This Note covers taking an appeal as of right, petitioning for permission to appeal, and posting cost bonds. This Note also explains the preliminary steps parties must complete before briefing, including preparing the record, ordering transcripts, filing required post-initiation documents, and participating in the DC Circuit's Appellate Mediation Program. It also briefly discusses special considerations for DC Circuit appeals from federal administrative agencies.