A Practice Note discussing how the Food and Drug Administration (FDA) regulates the transportation of human and animal food in the US to ensure it is safe, as required by the Sanitary Food Transportation Act of 2005 (SFTA) and the FDA Food Safety Modernization Act (FSMA). This Note discusses the FDA's sanitary food transportation requirements for shippers, loaders, carriers, and receivers of food, including vehicle and equipment maintenance, transportation operations, personnel training, and recordkeeping requirements.