A Practice Note describing the World Trade Organization's (WTO) mechanism for resolving trade disputes between member countries. This Note addresses the WTO's rules and procedures for settling disputes, including how to initiate an action before the WTO Dispute Settlement Body (DSB), appealing decisions to the WTO Appellate Body, and the tools for ensuring that countries comply with WTO decisions, such as WTO-authorized retaliatory measures. The Note also discusses the Multi-Party Interim Appeal Arbitration Arrangement (MPIA), which certain WTO members established as an alternative means of dispute settlement given the Appellate Body's current lack of a quorum to hear appeals of DSB panel reports.